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Bovine (Bos taurus).
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.
MTVFLSFAFL | AAILTHIGCS | NQRRSPENGG | RRYNRIQHGQ | CAYTFILPEH |
DGNCRESTTD | QYNTNALQRD | APHVEQDFSS | QKLQHLEHVM | ENYTQWLQKI |
ENYIVENMKS | EMAQIQQNAV | QNHTATMLEI | GTSLLSQTAE | QTRKLTDVET |
QVLNQTSRLE | IQLLENSLST | YKLEKQLLQQ | TNEILKIHEK | NSLLEHKIFE |
MEGKHKEELD | TLKEEKENLQ | GLVTRQTYII | QELEKQLNRA | TTNNSVLQKQ |
QLELMDTVHN | LVNLCTKEVL | LKGGKKEEEK | PFRDCADVYQ | AGFNKSGIYT |
IYINNMPEPK | KVFCNMDLNG | GGWTVIQHRE | DGSLDFQRGW | KEYKMGFGNP |
SGEYWLGNEF | IFAITSQRQY | TLRIELLDWE | GNRAYSQYDR | FHIGNEKQNY |
RLYLKGHTGT | AGKQSSLILH